The Organ Procurement and Transplantation Network (OPTN) has periodically revamped its organ allocation policies over the years to prioritize sicker children over adults and expand the geographic area of donors. A recent study led by Children鈥檚 Hospital Los Angeles showed that this has helped improve the odds for children with PALF.
A new AI tool is providing a sci-fi level of precision to physicians reviewing images of people鈥檚 livers, spleens, kidneys, and more to determine with some exactitude if they are showing any abnormal traits that could shorten a person鈥檚 life
Research roundup: How alcohol-associated liver disease differs among races; Esketamine shows promise for treatment-resistant depression; COVID-19鈥檚 effects on individual employment; EEG testing shows possible biomarker for suicidal ideation
The incidence of non-alcoholic fatty liver disease (NAFLD) and alcohol-associated liver disease (ALD) is increasing year by year due to changes in the contemporary environment and dietary structure, and is an important public health problem
The #HOPE4LIVER trials, testing the safety efficacy of histotripsy as a treatment for primary and metastatic liver tumors, met its goals for technical success and safety. An expert is quoted explaining the results.
People with alcohol use disorder (AUD) who are at risk of advanced liver disease are less likely to be referred for liver evaluation and care if they present primarily with alcohol-related mental health issues or a mental health diagnosis, according to a study of referral practices in Virginia鈥檚 largest health system. The findings point to the possibility of widespread missed opportunities for treating three conditions that commonly co-occur: AUD, mental health disorders, and liver disease. Recent years have seen notable increases in the USA in alcohol-related deaths, mental health disorders, and hospital admissions relating to alcohol use and concurrent mental health conditions. AUD is a significant cause of liver disease, and both addiction and co-occurring mental illness can be barriers to successful liver treatment. Integrating AUD treatment, mental health care, and hepatology (liver care) is necessary to improve outcomes, but data suggests this approach is not the norm. For the st
Research from the University of Michigan suggests that one day a phone app could be able to detect the development of hepatic encephalopathy in patients just by listening to them speak.
Receiving a liver transplant means also living with the possibility of rejection. Transplant rejection occurs when the body鈥檚 immune system attacks the new organ. This risk is highest in the first year after the transplant, but rejection can happen at any time. To prevent this, patients take powerful medications to suppress their immune system and reduce inflammation.
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Formerly known as nonalcoholic steatohepatitis, metabolic dysfunction-associated steatohepatitis (MASH) is an inflammatory disease characterized by liver scarring or fibrosis that progressively impairs liver function.
It is a major risk factor for cirrhosis and liver cancer. And because treatment options are limited, MASH is the second leading cause for liver transplants in the United States after cirrhosis caused by chronic hepatitis C infection.
A better understanding of the pathological processes that drive MASH is critical to creating effective treatments. In a new paper published August 19, 2024 in PNAS, a team of scientists from Sanford Burnham Prebys, the University of California San Diego School of Medicine and elsewhere, describe the complex interplay between diseased liver cells and macrophages 鈥� a type of white blood cell whose jobs include killing and removing harmful cells and pathogens and helping to spur normal healing.
The University of Texas MD Anderson Cancer Center鈥檚 Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson鈥檚 world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back.
Drugs such as Ozempic, Rybelsus and Wegovy have made news for their abilities to treat diabetes and encourage weight loss. To give a clearer understanding of the benefits and risks of GLP-1 agonists for patients with liver disease, Robert Fontana, M.D.,鈥痑 Michigan Medicine hepatologist, answered our questions.
The August issue of AJG includes articles on IBD, including the use of telehealth and added risks for RSV hospitalization, and the updated nomenclature for metabolic dysfunction-associated steatotic liver disease (MASLD).
People suffering from cirrhosis may find some symptom relief from two accessible activities: stretching and meditation.聽A study from the University of Michigan compared the two therapies as a means to relieve nocturnal muscle cramps and found both effective.聽
Taghreed Mohammed Al-Turki, PhD, a postdoctoral researcher in the UNC Lineberger lab of Jack Griffith, PhD, describes her long, difficult, and rewarding journey of becoming a telomere scientist as a first-time mother at the University of North Carolina School of Medicine.
Removing a nuclear bile acid receptor that regulates glucose and lipid stability from the intestine blocked gut inflammation in mice, according to researchers at Children鈥檚 Hospital Los Angeles.
An Indiana University School of Medicine physician scientist is making strides in understanding the molecular origins of fatty liver disease, a leading cause of liver failure in the United States.
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