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Cleveland Clinic Researchers Build First Large-Scale Atlas of How Immune Cells React to Mutations During Cancer Immunotherapy

Cleveland Clinic — Tue, 01 Oct 2024 16:05:57 EST

A Cleveland Clinic-led research collaboration between Timothy Chan, MD, PhD, Chair of Cleveland Clinic's Global Center for Immunotherapy, and Bristol Myers Squibb has published the most comprehensive overview to date of how our immune system reshapes tumor architecture in response to immune checkpoint therapy. The eight-year study, published in Nature Medicine, outlines how cancer immunotherapy induces tumor recognition through neoantigens to reshape the tumor ecosystem.

Cleveland Clinic Researchers Discover New Bacterium that Causes Gut Immunodeficiency

Cleveland Clinic — Thu, 26 Sep 2024 14:00:00 EST

Cleveland Clinic researchers have discovered a new bacterium that weakens the immune system in the gut, potentially contributing to certain inflammatory and infectious gut diseases. The team identified the bacterium, Tomasiella immunophila (T. immunophila), which plays a key role in breaking down a crucial immune component of the gut's multi-faceted protective immune barrier. Identifying this bacterium is the first step to developing new treatments for a variety of inflammatory and infectious gut diseases.

Cleveland Clinic Study Shows Bariatric Surgery Outperforms GLP-1 Diabetes Drugs for Kidney Protection

Cleveland Clinic — Fri, 20 Sep 2024 14:05:33 EST

Friday, September 20, 2024, CLEVELAND: A Cleveland Clinic study showed that in patients with type 2 diabetes, obesity, and chronic kidney disease, bariatric surgery was associated with a significant decrease in the progression of chronic kidney disease compared to those who received GLP-1 diabetes medications. The paper was published in Annals of Surgery.

Cleveland Clinic Study Is First to Show Success in Treating Rare Blood Disorder

Cleveland Clinic — Wed, 18 Sep 2024 17:00:00 EST

CLEVELAND: A clinical trial has demonstrated that the cancer drug pomalidomide is safe and effective in treating hereditary hemorrhagic telangiectasia (HHT), a rare bleeding disorder that impacts more than 1 in 5,000 people worldwide.

Research Assesses Impact of Weight Loss and Blood Sugar Control in Type 2 Diabetes

Cleveland Clinic — Tue, 17 Sep 2024 09:05:48 EST

Cleveland Clinic Study Identifies Key Factors That Can Impact Long-Term Weight Loss in Patients with Obesity Who Were Prescribed GLP-1 RA Medications

Cleveland Clinic — Fri, 13 Sep 2024 11:00:00 EST

Cleveland Clinic Study Identifies Key Factors That Can Impact Long-Term Weight Loss in Patients with Obesity Who Were Prescribed GLP-1 RA Medications

A Cleveland Clinic-Led Study Published in Clinical Infectious Diseases Examined How the 2019 ATS/IDSA Guidelines Would Have Applied to Adult Patients with Community-Acquired Pneumonia.

Cleveland Clinic — Wed, 11 Sep 2024 11:05:19 EST

National Cleveland Clinic Survey Examines Generational Divide in Men's Health

Cleveland Clinic — Wed, 04 Sep 2024 00:05:00 EST

National Cleveland Clinic Survey Examines Generational Divide in Men's Health

Study evaluates factors associated with delayed time to treatment in multiple myeloma

Cleveland Clinic — Thu, 29 Aug 2024 16:05:27 EST

Cleveland Clinic expert: Study to develop a blood-based lung cancer detection test published in Cancer Discovery

Cleveland Clinic — Tue, 27 Aug 2024 16:05:40 EST

Gut microbial pathway identified as target for improved heart disease treatment

Cleveland Clinic — Tue, 20 Aug 2024 10:05:49 EST

Cleveland Clinic researchers have made a significant discovery about how the gut microbiome interacts with cells to cause cardiovascular disease.

Cleveland Clinic study reveals diet as main risk factor for colon cancer in younger adults

Cleveland Clinic — Wed, 14 Aug 2024 15:05:35 EST

A new Cleveland Clinic study has identified diet-derived molecules called metabolites as main drivers of young-onset colorectal cancer risk, especially those associated with red and processed meat. The NPJ Precision Oncology report, which analyzed metabolite and microbiome datasets, highlighted that one of the best ways a younger (<60 years) adult can prevent colorectal cancer is to discuss their diet with their doctor.

Cleveland Clinic Partners with Sports Data Labs to Advance Sports Data Collection and Care for Athletes and Patients

Cleveland Clinic — Wed, 14 Aug 2024 10:00:27 EST

Cleveland Clinic and Sports Data Labs, Inc. (SDL) are partnering with the goal of creating the largest compilation of sports health data, which will be used to develop new technology-driven tools and services.

Study by Cleveland Clinic, Tufts University Highlights Potential for Using TMAO -- a Digestive By-Product -- to Predict Heart Failure Risk

Cleveland Clinic — Wed, 14 Aug 2024 09:05:21 EST

New Cleveland Clinic and Tufts University research shows that elevated levels of the gut microbiome trimethylamine N-oxide (TMAO) pathway led to a higher risk of heart failure independent of other risk factors, according to a study of two large National Institutes of Health cohorts. The study was recently published in the journal Circulation: Heart Failure.

Cleveland Clinic Study Adds to Increasing Evidence that Sugar Substitute Erythritol Raises Cardiovascular Risk

Cleveland Clinic — Thu, 08 Aug 2024 05:00:00 EST

New Cleveland Clinic research shows that consuming foods with erythritol, a popular artificial sweetener, increases risk of cardiovascular events such as heart attack and stroke. The findings, from a new intervention study in healthy volunteers, show erythritol made platelets (a type of blood cell) more active, which can raise the risk of blood clots.

Cleveland Clinic lidera investigacion cientifica que identifica zonas de prioridad para ayudar en la deteccion del cancer colorrectal entre latinos

Cleveland Clinic — Thu, 01 Aug 2024 11:05:04 EST

31 de julio de 2024, CLEVELAND - Un estudio desarrollado por Cleveland Clinic ha identificado areas geograficas en Estados Unidos, donde los esfuerzos estrategicos para promover la deteccion del cancer colorrectal podrian ayudar a reducir las brechas en la atencion medica que afectan a las comunidades hispanas/latinas.

Cleveland Clinic-led Research Identifies Priority Zones That May Help Improve Colorectal Cancer Screening Among Hispanic/Latino Individuals

Cleveland Clinic — Wed, 31 Jul 2024 13:00:50 EST

Cleveland Clinic-led research has identified geographic areas in the United States where strategic efforts to promote colorectal cancer screening could help reduce healthcare gaps affecting Hispanic/Latino communities. The study, published in the American Journal of Public Health, marks a first step toward conducting larger neighborhood-level studies addressing disparities in colorectal cancer screening.

Walsh University Announces Multi-Year Partnership with Cleveland Clinic Mercy Hospital Sports Medicine

Cleveland Clinic — Mon, 29 Jul 2024 10:55:27 EST

Walsh University has signed a major multi-year agreement with Cleveland Clinic Mercy Hospital Sports Medicine, strengthening a strong collaboration to enhance the health and wellness of its student scholar athletes.

Prenatal Zika infection has long-term immune consequences in children, even without microcephaly

Cleveland Clinic — Thu, 18 Jul 2024 13:05:05 EST

A Cleveland Clinic-led study published in eBioMedicine reveals that maternal Zika virus infections can reprogram fetal immune development, leading to long-term consequences in children's immunity.

Kent State and Cleveland Clinic Enter Multiyear Partnership to Support Student-Athlete Health and Wellness

Cleveland Clinic — Wed, 17 Jul 2024 10:05:33 EST

Kent State University and Cleveland Clinic have announced a multiyear partnership in which Cleveland Clinic becomes the official healthcare provider for Kent State Athletics.

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Cleveland Clinic Researchers Build First Large-Scale Atlas of How Immune Cells React to Mutations During Cancer Immunotherapy

Cleveland Clinic Researchers Discover New Bacterium that Causes Gut Immunodeficiency

Cleveland Clinic Study Shows Bariatric Surgery Outperforms GLP-1 Diabetes Drugs for Kidney Protection

Cleveland Clinic Study Is First to Show Success in Treating Rare Blood Disorder

Research Assesses Impact of Weight Loss and Blood Sugar Control in Type 2 Diabetes

Cleveland Clinic Study Identifies Key Factors That Can Impact Long-Term Weight Loss in Patients with Obesity Who Were Prescribed GLP-1 RA Medications

A Cleveland Clinic-Led Study Published in Clinical Infectious Diseases Examined How the 2019 ATS/IDSA Guidelines Would Have Applied to Adult Patients with Community-Acquired Pneumonia.

National Cleveland Clinic Survey Examines Generational Divide in Men's Health

Study evaluates factors associated with delayed time to treatment in multiple myeloma

Cleveland Clinic expert: Study to develop a blood-based lung cancer detection test published in Cancer Discovery

Gut microbial pathway identified as target for improved heart disease treatment

Cleveland Clinic study reveals diet as main risk factor for colon cancer in younger adults

Cleveland Clinic Partners with Sports Data Labs to Advance Sports Data Collection and Care for Athletes and Patients

Study by Cleveland Clinic, Tufts University Highlights Potential for Using TMAO -- a Digestive By-Product -- to Predict Heart Failure Risk

Cleveland Clinic Study Adds to Increasing Evidence that Sugar Substitute Erythritol Raises Cardiovascular Risk

Cleveland Clinic lidera investigacion cientifica que identifica zonas de prioridad para ayudar en la deteccion del cancer colorrectal entre latinos

Cleveland Clinic-led Research Identifies Priority Zones That May Help Improve Colorectal Cancer Screening Among Hispanic/Latino Individuals

Walsh University Announces Multi-Year Partnership with Cleveland Clinic Mercy Hospital Sports Medicine

Prenatal Zika infection has long-term immune consequences in children, even without microcephaly

Kent State and Cleveland Clinic Enter Multiyear Partnership to Support Student-Athlete Health and Wellness

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