ŷ��Ʒ Feature Channel: Clinical Trials

Demystifying APE1: New findings on direct activation of ATM signaling by DNA single-strand breaks

University of North Carolina at Charlotte — Thu, 08 Aug 2024 14:05:18 EST

Whereas ATM signaling is well known to be activated by DNA doubles-strand breaks, this study provides new evidence that ATM signaling is directly activated by DNA single-strand breaks and activated and regulated by APE1 in eukaryotic systems.

Mercy Medical Center Receives Joint Commission's Core Certification for Spinal Surgery

Mercy Medical Center — Thu, 08 Aug 2024 12:05:28 EST

The Joint Commission has awarded core certification for spinal surgery to Mercy Medical Center in Baltimore, Maryland, for demonstrating compliance with its performance standards.

Expert available to speak about how Olympic athletes get medical support during the Games

Northern Arizona University — Wed, 07 Aug 2024 16:05:37 EST

National Academies progress report: health disparities

University of California, Irvine — Wed, 07 Aug 2024 15:05:59 EST

From costing society an estimated $11 trillion to hindering new discoveries in medicine and preventing access to effective interventions, underrepresentation of women, older adults and minorities in clinical research has several significant consequences, according to recent analyses commissioned by the National Academies of Sciences, Engineering and Medicine.

Adding metastasis-directed radiation therapy boosts progression-free survival in metastatic pancreatic cancer

University of Texas MD Anderson Cancer Center — Mon, 05 Aug 2024 16:00:00 EST

Researchers from The University of Texas MD Anderson Cancer Center demonstrated that adding metastasis-directed radiation therapy to standard-of-care chemotherapy improved progression-free survival (PFS) in patients with oligometastatic pancreatic cancer.

UCLA Health launches clinical trial using personalized cancer vaccine to tackle aggressive brain tumors in adolescents and young adults

University of California, Los Angeles (UCLA), Health Sciences — Mon, 05 Aug 2024 11:05:04 EST

In an effort to combat one of the most lethal forms of pediatric brain cancer, researchers at the UCLA Health Jonsson Comprehensive Cancer Center are launching a first-of-its-kind clinical trial to evaluate the safety and effectiveness of a cancer vaccine targeting H3 G34-mutant diffuse hemispheric glioma, a highly aggressive brain tumor that is typically found in adolescents and young adults.

James (Chip) F. Howard, Jr., MD, Receives AANEM's 2024 Lifetime Achievement Award

American Association of Neuromuscular and Electrodiagnostic Medicine (AANEM) — Thu, 01 Aug 2024 10:05:42 EST

The American Association of Neuromuscular & Electrodiagnostic Medicine (AANEM) proudly announces Chip F. Howard, Jr., MD, as the 2024 Lifetime Achievement Award winner. This award is the highest honor bestowed by AANEM and recognizes major contributors in neuromuscular (NM) and electrodiagnostic (EDX) medicine.

UC Irvine Institute for Clinical & Translational Science receives $28 million NIH grant

University of California, Irvine — Wed, 31 Jul 2024 18:05:06 EST

The Institute for Clinical & Translational Science at the University of California, Irvine has been awarded $28,394,693 over seven years from the National Institutes of Health as part of its Clinical & Translational Science Awards Program.

Treatment for Recurrent Uterine Cancer Advances to Next Research Phase

Yale Cancer Center/Smilow Cancer Hospital — Wed, 31 Jul 2024 16:05:40 EST

The latest trial of a new antibody drug that delivers potent chemotherapy directly to cancer cells for patients with advanced or recurrent endometrial cancer moves ahead to be studied further in a phase III trial.

New Survey Reveals Burnout in Clinical Labs Impacts Patient Care, Staff Safety; Optimism that Automation, AI Will Help Tackle Challenges

ADLM 2024 Press Program — Wed, 31 Jul 2024 13:05:24 EST

U.S. survey from Siemens Healthineers and The Harris Poll indicates laboratory staff are looking for greater support from automation and AI to offset negative side effects of prolonged understaffing.

New test can detect patients' risk of harmful side effects from Alzheimer's drugs

Association for Diagnostic and Laboratory Medicine (ADLM (formerly AACC)) — Wed, 31 Jul 2024 10:30:00 EST

Today at ADLM 2024 (formerly the AACC Annual Scientific Meeting & Clinical Lab Expo), researchers will present data on a novel test that predicts whether Alzheimer's patients are genetically predisposed to side effects from anti-amyloid drugs, a promising new class of Alzheimer's therapeutics.

Brain cell grafts in monkeys jump-start human trial for new Parkinson's treatment

University of Wisconsin-Madison — Mon, 29 Jul 2024 09:05:21 EST

People with Parkinson's disease are receiving a new treatment in a clinical trial started after University of Wisconsin-Madison scientists demonstrated the safety and feasibility of the therapeutic delivery method in a study of non-human primates.

The consequences of ending abortion protection, the patient perspective on laboratory developed tests, health equity, and more to be explored at ADLM 2024

Association for Diagnostic and Laboratory Medicine (ADLM (formerly AACC)) — Sun, 28 Jul 2024 18:00:00 EST

At ADLM 2024 (formerly the AACC Annual Scientific Meeting & Clinical Lab Expo) in Chicago, more than 300 experts will present cutting-edge research and technology that will shape the future of laboratory medicine and improve patient care.

Study Identifies Biomarker that Could Predict Whether Colon Cancer Patients Benefit from Chemotherapy

Sylvester Comprehensive Cancer Center — Fri, 26 Jul 2024 16:05:45 EST

A new study identifies and validates a 10-gene biomarker that potentially predicts whether a stage II or III colon cancer patient will benefit from adjuvant chemotherapy. A secondary finding from the study suggests that the gene signature could potentially also predict whether immunotherapy would help some patients.

Recent insights and advances in treatment and management show promise in stemming the growing prevalence of diabetes

University of California, Los Angeles (UCLA), Health Sciences — Fri, 26 Jul 2024 15:05:40 EST

A new paper surveying advances in diabetes pathogenesis and treatment explores the complex factors contributing to the onset and progression of the disease, suggesting that an understanding of these dynamics is key to developing targeted interventions to reduce the risk of developing diabetes and managing its complications.

Posterior surgery is noninferior to anterior surgery for cervical radiculopathy

Wolters Kluwer Health: Lippincott — Thu, 25 Jul 2024 13:40:27 EST

For patients with cervical radiculopathy, posterior foraminotomy provides outcomes comparable to those of the more commonly performed anterior cervical discectomy, reports a randomized clinical trial in The Journal of Bone & Joint Surgery. The journal is published in the Lippincott portfolio by Wolters Kluwer.

bioMerieux receives U.S. FDA Special 510(k) clearance and CLIA-waiver for its BIOFIRE(r) SPOTFIRE(r) Respiratory/Sore Throat (R/ST) Panel Mini

ADLM 2024 Press Program — Wed, 24 Jul 2024 12:15:02 EST

bioMerieux, a world leader in the field of in vitro diagnostics, today announces that its BIOFIRE(r) SPOTFIRE(r) Respiratory/Sore Throat (R/ST) Panel Mini has received U.S. Food and Drug Administration (FDA) Special 510(k) clearance and CLIA-waiver (Clinical Laboratory Improvement Amendments).

AMR Expands Clinical Research Offerings in the Carolinas with Waccamaw Dermatology Partnership

Alliance for Multispecialty Research (AMR) — Thu, 18 Jul 2024 08:05:11 EST

Alliance for Multispecialty Research (AMR), a leading clinical research site company, and Waccamaw Dermatology, renowned for its comprehensive, specialized dermatological care as one of the largest physician-owned and led dermatology practices in the Carolinas, today announced a strategic partnership that expands access to clinical trials in the Carolinas.

Participate in Study to Reduce Disparate Growth of Alzheimer's Disease in Black Population

Corewell Health — Mon, 15 Jul 2024 20:05:31 EST

Corewell Health is working with Johns Hopkins Bloomberg School of Public Health and North Carolina Agricultural and Technical State University to learn more about the multi-level risk and biopsychosocial factors that contribute to Alzheimer's disease in Black Americans, leading to the development of effective, tailored behavioral and pharmacological interventions aimed at reducing the condition's disparate attack.

Clinical-grade microbiome drug manufacturing facility opens at UChicago

University of Chicago Medical Center — Mon, 15 Jul 2024 14:05:57 EST

The first of its kind at an academic institution, the facility gives experts the capability to put live bacteria into capsules that can be administered safely to patients in clinical trials.

ŷ����Ʒ Feature Channel: Clinical Trials