With a rapidly aging global population, investing in longevity science can bridge the 10鈥搚ear gap between lifespan and healthspan. A breakthrough could save trillions in healthcare costs, improving health outcomes and economic resilience for all, writes Dr. Mehmood Khan.
In a world where global life expectancy is forecasted to increase from 73.6 years in 2022 to 78.1 years by 2050, the focus is shifting from merely extending lifespan to enhancing healthspan 鈥� the number of years lived in good health. At the forefront of this paradigm shift is Hevolution Foundation, a non-profit organization based out of Riyadh, Saudi Arabia - with an unprecedented commitment of up to $1 billion annually to revolutionize the field of aging research.
Longevity research is focussed on extending our time in good health, with the goal of increasing healthspan鈥攖he years spent in optimal well-being鈥攔ather than simply adding more years to life.
We鈥檙e living much longer than our ancestors, but is that always a good thing? With many people living well into our late 70s or beyond, more of us are also spending a greater portion of our lives鈥攕ometimes a decade or more鈥攕addled with physical and mental health conditions that can make it challenging to accomplish the tasks of daily life.
Northwestern University has been awarded $32.4 million over five years from the Hevolution Foundation to study proteostasis 鈥� the processes by which cells maintain protein health for good overall health and to prevent diseases of protein misfolding. A key goal is to improve the health people experience as they age, particularly in their final years.
Hevolution Foundation and Dolby Family Ventures led Vandria鈥檚 Series A closing, bringing the capital to CHF 28.3. With the money, the 2021 EFPL spin-out aims to advance its first in class mitophagy inducer VNA-318 that targets several neurodegenerative indications into clinical development.
What if a drug could help you live a longer, healthier life? Scientists at the University of Connecticut are working on it. In a new study in Cell Metabolism, researchers described how to target specific cells to extend the lifespan and improve the health of mice late in life.
Hevolution Foundation, a global nonprofit organization that provides grants and early-stage investments to incentivize research and entrepreneurship in healthspan science, has committed over $400 million to healthspan sciences within the past 21 months, positioning the Foundation as the world's largest philanthropic funder of geroscience.
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