Researchers at the National Institutes of Health (NIH) and their collaborators have identified a protein, known as RNF114, that reverses cataracts, a clouding of the eye鈥檚 lens that occurs commonly in people as they age.
Trachomatous trichiasis, a potentially blinding condition where inward-turned eyelashes scratch the front of the eye, can successfully be treated by either of the two most common types of eyelid surgery, according to findings from a large comparison trial funded by the National Institutes of Health.
Monkeypox virus (mpoxv) has re-emerged, designated on August 14 as a global emergency by the World Health Organization. Newly evolved strains of mpox viruses can efficiently spread among people. In addition to skin rashes, mpox infection can cause eye complications including inflammation of the clear tissue covering the iris and pupil called the cornea (keratitis), the tissue covering the white of the eye and the underside of the eyelid (conjunctivitis, or pink eye), and the eyelid (blepharitis).
In a new analysis of data, researchers at the National Institutes of Health (NIH) have found that taking a daily supplement containing antioxidant vitamins and minerals slows progression of late-stage dry age-related macular degeneration (AMD), potentially helping people with late-stage disease preserve their central vision.
Scientists at the National Institutes of Health (NIH) have uncovered a brain circuit in primates that rapidly detects faces. The findings help not only explain how primates sense and recognize faces, but could also have implications for understanding conditions such as autism, where face detection and recognition are often impaired from early childhood.
Research led by scientists at the National Eye Institute and Sun Yat-sen University, Guangzhou, China points to a potential strategy for extending the cold storage shelf life of donor cells and tissues, such as those of the pancreas, an organ crucial for making insulin.
Findings from a National Eye Institute-supported study show for the first time that when babies look at photos of unfamiliar everyday scenes, such as an office or a lab, they tend to fixate on the same regions where adults find meaning. This inclination to home in on what鈥檚 interesting or meaningful grows more pronounced as babies age. The findings, published in Infancy, provide a more nuanced understanding of visual development, which may lead to earlier detection of brain-based causes of vision problems, such as cerebral/cortical visual impairment.
National Eye Institute researchers studying human retinas discovered 87 target genes where a mix of environmental factors likely influence one鈥檚 risk of developing age-related macular degeneration (AMD), a leading cause of vision loss in people ages 65 and older.
The drug minocycline, an antibiotic that also decreases inflammation, failed to slow vision loss or expansion of geographic atrophy in people with dry age-related macular degeneration (AMD), according to a phase II clinical study at the National Eye Institute (NEI), part of the National Institutes of Health.
Researchers at the National Eye Institute (NEI) have improved a crucial step in the production of retinal pigment epithelium (RPE), a tissue they grow in the lab from patient blood cells and are testing in a clinical trial as treatment for age-related macular degeneration (AMD).
Glaucoma remains one of the most common causes of vision loss and blindness in the U.S. and much of the world, disproportionately affecting older people, African Americans, and Hispanics and Latinos.
The Noelin family of secreted proteins bind to the external portion of AMPA glutamate receptors and stabilize them on the neuronal cellular membrane, a process necessary for transmission of full-strength signals between neurons, according to a study in mice from the National Eye Institute (NEI) and the University of Freiberg, Germany.
Repeat treatment with corticosteroid injections improved vision in people with persistent or recurrent uveitis-related macular edema better than two other therapies, according to results from a clinical trial funded by the National Eye Institute (NEI).
Researchers at NIH鈥檚 National Eye Institute have published a detailed protocol for making three cell types that are key components to form blood vessels and capillaries.
A study from the National Eye Institute (NEI) identified rare genetic variants that could point to one of the general mechanisms driving age-related macular degeneration (AMD), a common cause of vision loss in older adults.
A National Eye Institute-led team has identified a compound already approved by the U.S. Food and Drug Administration that keeps light-sensitive photoreceptors alive in three models of Leber congenital amaurosis type 10 (LCA 10), an inherited retinal ciliopathy disease that often results in severe visual impairment or blindness in early childhood.
Using vision to efficiently move through an area by foot uses a unique region of the brain鈥檚 cortex, according to a small study funded by the National Eye Institute (NEI).
Researchers supported by the National Eye Institute are developing artificial intelligence/machine learning (AI/ML)-based systems that not only screen for AMD but also predict which patients will likely progress to late within two years. The systems also evaluate separately one鈥檚 risk for developing late wet (neovascular) AMD from one鈥檚 risk for late dry (geographic atrophy) AMD.
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